InnateDB Protein
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IDBP-592761.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RGS13
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Protein Name
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regulator of G-protein signaling 13
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000442837
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InnateDB Gene
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IDBG-105448 (RGS13)
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Protein Structure
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Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)- alpha (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
GO:0007186
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G-protein coupled receptor signaling pathway
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GO:0008277
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regulation of G-protein coupled receptor protein signaling pathway
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GO:0038032
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termination of G-protein coupled receptor signaling pathway
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GO:0043547
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positive regulation of GTPase activity
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GO:0045744
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negative regulation of G-protein coupled receptor protein signaling pathway
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Cellular Component |
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PDB ID |
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InterPro |
IPR000342
Regulator of G protein signalling domain
IPR016137
Regulator of G protein signalling superfamily
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PFAM |
PF00615
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PRINTS |
PR01301
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PIRSF |
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SMART |
SM00315
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TIGRFAMs |
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Modification |
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SwissProt |
O14921
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PhosphoSite |
PhosphoSite-O14921
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TrEMBL |
A0A024R989
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UniProt Splice Variant |
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Entrez Gene |
6003
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UniGene |
Hs.497220
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RefSeq |
NP_658912
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HUGO |
HGNC:9995
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OMIM |
607190
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CCDS |
CCDS1376
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HPRD |
06222
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IMGT |
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EMBL |
AF030107
AF493935
AL136454
AL596119
AY562947
BC016667
BC056866
BT006929
CH471067
CR536532
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GenPept |
AAB84000
AAH16667
AAH56866
AAM12649
AAP35575
AAS66360
CAG38769
CAH71773
CAI17062
EAW91229
EAW91230
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