Version 5.4
Homo sapiens Protein: AMICA1
Summary
InnateDB Protein IDBP-593566.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMICA1
Protein Name adhesion molecule, interacts with CXADR antigen 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000431218
InnateDB Gene IDBG-73536 (AMICA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0007157 heterophilic cell-cell adhesion
GO:0007596 blood coagulation
GO:0030593 neutrophil chemotaxis
GO:0035696 monocyte extravasation
GO:0046629 gamma-delta T cell activation
GO:0050776 regulation of immune response
GO:0050900 leukocyte migration
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0072672 neutrophil extravasation
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86YT9
PhosphoSite PhosphoSite-Q86YT9
TrEMBL E9PNS8
UniProt Splice Variant
Entrez Gene 120425
UniGene Hs.657856
RefSeq NP_001273500
HUGO HGNC:19084
OMIM 609770
CCDS CCDS66240
HPRD 16482
IMGT
EMBL AJ515553 AK090409 AK094399 AP002800 AY093686 AY138965 AY358362 BC100797 EF444945
GenPept AAI00798 AAM15730 AAN52117 AAQ88728 ACA05929 ACA05930 BAC03390 BAC04347 CAD56620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca