Version 5.4
Homo sapiens Gene: AMICA1
Summary
InnateDB Gene IDBG-73536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMICA1
Gene Name adhesion molecule, interacts with CXADR antigen 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160593
Encoded Proteins
IDBP-73538
adhesion molecule, interacts with CXADR antigen 1
IDBP-73540
adhesion molecule, interacts with CXADR antigen 1
IDBP-586752
adhesion molecule, interacts with CXADR antigen 1
IDBP-591531
adhesion molecule, interacts with CXADR antigen 1
IDBP-593566
adhesion molecule, interacts with CXADR antigen 1
IDBP-596571
adhesion molecule, interacts with CXADR antigen 1
IDBP-598765
adhesion molecule, interacts with CXADR antigen 1
IDBP-603167
adhesion molecule, interacts with CXADR antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118193740-118225094
Strand Reverse strand
Band q23.3
Transcripts
ENST00000292067 ENSP00000292067
ENST00000356289 ENSP00000348635
ENST00000534294
ENST00000533261 ENSP00000436117
ENST00000526595 ENSP00000431614
ENST00000531530
ENST00000526620 ENSP00000431218
ENST00000529164
ENST00000531536
ENST00000524477 ENSP00000432769
ENST00000527877 ENSP00000435145
ENST00000525565 ENSP00000431791
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0007157 heterophilic cell-cell adhesion
GO:0007596 blood coagulation
GO:0030593 neutrophil chemotaxis
GO:0035696 monocyte extravasation
GO:0046629 gamma-delta T cell activation
GO:0050776 regulation of immune response
GO:0050900 leukocyte migration
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0072672 neutrophil extravasation
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048534
View Gene Order
ENSBTAG00000023283
Not yet available
Pathways
NETPATH
REACTOME
REACT_11152
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
integrin_a4b1_pathway
Alpha4 beta1 integrin signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.16291 Hs.657856
RefSeq NM_001098526 NM_001286570 NM_001286571 NM_153206 XM_005271406 XM_005271407
HUGO
OMIM
CCDS CCDS41723 CCDS66240 CCDS8391
HPRD 16482
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca