Version 5.4
Homo sapiens Protein: CAPN1
Summary
InnateDB Protein IDBP-593663.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPN1
Protein Name calpain 1, (mu/I) large subunit
Synonyms CANP; CANP1; CANPL1; muCANP; muCL;
Species Homo sapiens
Ensembl Protein ENSP00000435198
InnateDB Gene IDBG-56732 (CAPN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 97 [view]
Protein-Protein 97 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR001300 Peptidase C2, calpain, catalytic domain
IPR022684 Peptidase C2, calpain family
PFAM PF00648
PRINTS PR00704
PIRSF
SMART SM00230
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PLX0
UniProt Splice Variant
Entrez Gene 823
UniGene Hs.735492
RefSeq
HUGO HGNC:1476
OMIM 114220
CCDS
HPRD 00253
IMGT
EMBL AP003068
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca