InnateDB Protein
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IDBP-593935.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GTF2A1
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Protein Name
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general transcription factor IIA, 1, 19/37kDa
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Synonyms
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TF2A1; TFIIA; TFIIA-42; TFIIAL;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000452454
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InnateDB Gene
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IDBG-14595 (GTF2A1)
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Protein Structure
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Function |
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. {ECO:0000269PubMed:11030333, ECO:0000269PubMed:16537915}.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated |
Total |
50
[view]
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Protein-Protein |
50
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
15 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004855
Transcription factor IIA, alpha/beta subunit
IPR009083
Transcription factor IIA, helical
IPR009088
Transcription factor IIA, beta-barrel
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PFAM |
PF03153
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P52655
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PhosphoSite |
PhosphoSite-P52655
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
2957
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UniGene |
Hs.592334
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RefSeq |
NP_056943
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HUGO |
HGNC:4646
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OMIM |
600520
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CCDS |
CCDS9873
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HPRD |
02748
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IMGT |
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EMBL |
AC010582
BC107155
BC107156
D14886
D14887
X75383
X77225
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GenPept |
AAF26776
AAI07156
AAI07157
BAA03603
BAA03604
CAA53151
CAA53152
CAA54442
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