Version 5.4
Homo sapiens Protein: CLEC7A
Summary
InnateDB Protein IDBP-594004.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC7A
Protein Name C-type lectin domain family 7, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436923
InnateDB Gene IDBG-18428 (CLEC7A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008329 signaling pattern recognition receptor activity
GO:0030246 carbohydrate binding
GO:0042287 MHC protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006910 phagocytosis, recognition
GO:0006954 inflammatory response
GO:0008037 cell recognition
GO:0009756 carbohydrate mediated signaling
GO:0042110 T cell activation
GO:0042832 defense response to protozoan
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXN2
PhosphoSite PhosphoSite-Q9BXN2
TrEMBL
UniProt Splice Variant
Entrez Gene 64581
UniGene
RefSeq XP_005253525
HUGO HGNC:14558
OMIM 606264
CCDS
HPRD 08396
IMGT
EMBL AC024224 AF313468 AF313469 AF400595 AF400596 AF400597 AF400598 AF400599 AF400600 AF400601 AF400602 AJ312372 AJ312373 AK297028 AK298679 AK298724 AK313247 AY009090 AY026769 AY026770 AY026771 AY359002 BC013385 BC071746 BC093829 BC093831 CH471094
GenPept AAG33923 AAH13385 AAH71746 AAH93829 AAH93831 AAK20114 AAK20115 AAK20116 AAK37473 AAK37474 AAL11711 AAL11712 AAL11713 AAL11714 AAL11715 AAL11716 AAL11717 AAL11718 AAQ89361 BAG36058 BAH12480 BAH12845 BAH12855 CAC43846 CAC43847 EAW96144 EAW96145 EAW96146 EAW96150 EAW96154

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca