InnateDB Protein
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IDBP-59404.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZNF346
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Protein Name
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zinc finger protein 346
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Synonyms
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JAZ; Zfp346;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000350869
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InnateDB Gene
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IDBG-59400 (ZNF346)
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Protein Structure
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Function |
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. {ECO:0000269PubMed:24521053}.
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Subcellular Localization |
Nucleus, nucleolus {ECO:0000269PubMed:15254228}. Cytoplasm {ECO:0000269PubMed:15254228}. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
34
[view]
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Protein-Protein |
33
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
GO:0043065
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positive regulation of apoptotic process
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Cellular Component |
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PDB ID |
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InterPro |
IPR003604
Zinc finger, U1-type
IPR015880
Zinc finger, C2H2-like
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00451
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UL40
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PhosphoSite |
PhosphoSite-Q9UL40
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23567
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UniGene |
Hs.484259
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RefSeq |
NP_036411
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HUGO |
HGNC:16403
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OMIM |
605308
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CCDS |
CCDS4409
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HPRD |
05606
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IMGT |
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EMBL |
AC027314
AC027317
AF083340
AK131469
AK295549
BC007775
CR749692
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GenPept |
AAD52018
AAH07775
BAD18614
BAH12103
CAH18475
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