Version 5.4
Homo sapiens Protein: HES7
Summary
InnateDB Protein IDBP-594587.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HES7
Protein Name hairy and enhancer of split 7 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000446205
InnateDB Gene IDBG-27966 (HES7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008134 transcription factor binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001501 skeletal system development
GO:0001756 somitogenesis
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007219 Notch signaling pathway
GO:0007498 mesoderm development
GO:0014807 regulation of somitogenesis
GO:0036342 post-anal tail morphogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048511 rhythmic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003650 Orange
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF07527
PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BYE0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84667
UniGene
RefSeq NP_001159439
HUGO HGNC:15977
OMIM 608059
CCDS CCDS54085
HPRD 09729
IMGT
EMBL AB049064 AC129492 BC039887
GenPept BAB39525

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca