Version 5.4
Homo sapiens Protein: MACF1
Summary
InnateDB Protein IDBP-594833.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MACF1
Protein Name microtubule-actin crosslinking factor 1
Synonyms ABP620; ACF7; MACF; OFC4;
Species Homo sapiens
Ensembl Protein ENSP00000435078
InnateDB Gene IDBG-96610 (MACF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0016055 Wnt signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001715 Calponin homology domain
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF11971
PRINTS
PIRSF
SMART SM00033
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PLY0
UniProt Splice Variant
Entrez Gene 643314
UniGene Hs.723432
RefSeq
HUGO HGNC:13664
OMIM 608271
CCDS
HPRD 09750
IMGT
EMBL AL137853 AL355477 AL356055 AL365277 AL442071
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca