Homo sapiens Protein: CHRNA6 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-594917.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | CHRNA6 | ||||||||||||
Protein Name | cholinergic receptor, nicotinic, alpha 6 | ||||||||||||
Synonyms | CHNRA6; | ||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000433871 | ||||||||||||
InnateDB Gene | IDBG-20385 (CHRNA6) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | ||||||||||||
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR002394
Nicotinic acetylcholine receptor IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding |
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PFAM |
PF02932
PF02931 |
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PRINTS |
PR00254
PR00252 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q15825 | ||||||||||||
PhosphoSite | PhosphoSite-Q15825 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 8973 | ||||||||||||
UniGene | Hs.730178 | ||||||||||||
RefSeq | NP_001186208 | ||||||||||||
HUGO | HGNC:15963 | ||||||||||||
OMIM | 606888 | ||||||||||||
CCDS | CCDS56536 | ||||||||||||
HPRD | 06056 | ||||||||||||
IMGT | |||||||||||||
EMBL | AB079251 AC087533 AK298798 AK313521 BC014456 CH471080 U62435 Y16282 | ||||||||||||
GenPept | AAB40113 AAH14456 BAC06855 BAG36301 BAG60933 CAA76155 EAW63207 | ||||||||||||