Version 5.4
Homo sapiens Protein: SEC11A
Summary
InnateDB Protein IDBP-595044.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC11A
Protein Name SEC11 homolog A (S. cerevisiae)
Synonyms 1810012E07Rik; SEC11L1; sid2895; SPC18; SPCS4A;
Species Homo sapiens
Ensembl Protein ENSP00000452697
InnateDB Gene IDBG-27714 (SEC11A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006412 translation
GO:0006465 signal peptide processing
GO:0006508 proteolysis
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001733 Peptidase S26B, eukaryotic signal peptidase
IPR015927 Peptidase S24/S26A/S26B/S26C
IPR019759 Peptidase S24/S26A/S26B
PFAM PF00717
PRINTS PR00728
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P67812
PhosphoSite PhosphoSite-P67812
TrEMBL H0YNX5
UniProt Splice Variant
Entrez Gene 23478
UniGene Hs.9534
RefSeq NP_001258851
HUGO HGNC:17718
OMIM
CCDS CCDS61743
HPRD 07503
IMGT
EMBL AC087732 AC115102 AF061737 AF090315 AF108945 AK223224 AK300693 AK314146 BC000359 BC014508 CH471101
GenPept AAC36354 AAD17526 AAD19640 AAH00359 AAH14508 BAD96944 BAG36834 BAG62376 EAX01952 EAX01954 EAX01956

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca