InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP3CA

Summary

InnateDB Protein

IDBP-595180.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP3CA

Protein Name

protein phosphatase 3, catalytic subunit, alpha isozyme

Synonyms

CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B;

Species

Homo sapiens

Ensembl Protein

ENSP00000434599

InnateDB Gene

IDBG-31818 (PPP3CA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	66 [view]
Protein-Protein	64 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016787	hydrolase activity

Biological Process

GO:0045087

innate immune response (InnateDB)

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149

PRINTS

PR00114

PIRSF

SMART

SM00156

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt