Version 5.4
Homo sapiens Protein: IFNGR1
Summary
InnateDB Protein IDBP-595511.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFNGR1
Protein Name interferon gamma receptor 1
Synonyms CD119; IFNGR; IMD27A; IMD27B;
Species Homo sapiens
Ensembl Protein ENSP00000443282
InnateDB Gene IDBG-97020 (IFNGR1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 31 [view]
Protein-Protein 19 [view]
Protein-DNA 11 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019955 cytokine binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR015373 Interferon alpha/beta receptor, beta chain
IPR021126 Interferon gamma receptor, poxvirus/mammal
PFAM PF00041
PF01108
PF09294
PF07140
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5QBZ2
UniProt Splice Variant
Entrez Gene 3459
UniGene
RefSeq
HUGO HGNC:5439
OMIM 107470
CCDS
HPRD 00127
IMGT
EMBL EF173879 HQ670233 HQ670234 HQ670235 HQ670236 HQ670237
GenPept ABM53152 ADR72811 ADR72812 ADR72813 ADR72814 ADR72815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca