Version 5.4
Homo sapiens Protein: IST1
Summary
InnateDB Protein IDBP-595710.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IST1
Protein Name increased sodium tolerance 1 homolog (yeast)
Synonyms OLC1;
Species Homo sapiens
Ensembl Protein ENSP00000438399
InnateDB Gene IDBG-41285 (IST1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0032403 protein complex binding
GO:0090541 MIT domain binding
Biological Process
GO:0000910 cytokinesis
GO:0008104 protein localization
GO:0009838 abscission
GO:0019076 viral release from host cell
GO:0045184 establishment of protein localization
GO:0045862 positive regulation of proteolysis
GO:0046745 viral capsid secondary envelopment
GO:0048672 positive regulation of collateral sprouting
GO:0051301 cell division
Cellular Component
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005813 centrosome
GO:0005829 cytosol
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030496 midbody
GO:0070062 extracellular vesicular exosome
GO:0090543 Flemming body
Protein Structure and Domains
PDB ID
InterPro IPR005061 Domain of unknown function DUF292, eukaryotic
PFAM PF03398
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53990
PhosphoSite PhosphoSite-P53990
TrEMBL H3BUI0
UniProt Splice Variant
Entrez Gene 9798
UniGene
RefSeq NP_001257905
HUGO HGNC:28977
OMIM
CCDS CCDS59271
HPRD 13784
IMGT
EMBL AB097052 AC009127 AC010653 AK057258 AK293022 AK293040 AK297088 AK301918 BC000116 BC000430 BC004359 BC103745 D79996
GenPept AAH00116 AAH00430 AAH04359 AAI03746 BAA11491 BAC77405 BAF85711 BAF85729 BAG51894 BAG59603 BAG63341

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca