InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KDM2A

Summary

InnateDB Protein

IDBP-595718.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KDM2A

Protein Name

lysine (K)-specific demethylase 2A

Synonyms

CXXC8; FBL11; FBL7; FBXL11; JHDM1A; LILINA;

Species

Homo sapiens

Ensembl Protein

ENSP00000435776

InnateDB Gene

IDBG-59841 (KDM2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.

Experimentally validated
Total	25 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0051864	histone demethylase activity (H3-K36 specific)

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0055114	oxidation-reduction process
GO:0070544	histone H3-K36 demethylation

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

InterPro

IPR001810 F-box domain
IPR001965 Zinc finger, PHD-type
IPR002857 Zinc finger, CXXC-type
IPR006553 Leucine-rich repeat, cysteine-containing subtype
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00646
PF12937
PF13013
PF02008
PF00628

PRINTS

PIRSF

SMART

SM00256
SM00249
SM00367

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y2K7