Homo sapiens Protein: TRDN
Summary
InnateDB Protein IDBP-595851.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRDN
Protein Name triadin
Synonyms CPVT5; TDN; TRISK;
Species Homo sapiens
Ensembl Protein ENSP00000439281
InnateDB Gene IDBG-96065 (TRDN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0030674 protein binding, bridging
GO:0042803 protein homodimerization activity
GO:0044325 ion channel binding
Biological Process
GO:0006874 cellular calcium ion homeostasis
GO:0006936 muscle contraction
GO:0010649 regulation of cell communication by electrical coupling
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0014070 response to organic cyclic compound
GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0014902 myotube differentiation
GO:0031122 cytoplasmic microtubule organization
GO:0034220 ion transmembrane transport
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0055085 transmembrane transport
GO:0060047 heart contraction
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0086036 regulation of cardiac muscle cell membrane potential
GO:0090158 endoplasmic reticulum membrane organization
GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0014701 junctional sarcoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
GO:0030314 junctional membrane complex
GO:0033017 sarcoplasmic reticulum membrane
GO:0033018 sarcoplasmic reticulum lumen
GO:0034704 calcium channel complex
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR007943 Aspartyl beta-hydroxylase/Triadin domain
PFAM PF05279
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13061
PhosphoSite PhosphoSite-Q13061
TrEMBL H9ME53
UniProt Splice Variant
Entrez Gene 10345
UniGene Hs.720730
RefSeq NP_001242950
HUGO HGNC:12261
OMIM 603283
CCDS CCDS75511
HPRD 04474
IMGT
EMBL AL133257 AL357352 AL445259 AL603902 AL603911 BC070290 BC139910 JN900469 U18985
GenPept AAA75315 AAH70290 AAI39911 AEW10557