InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SNAPC3

Summary

InnateDB Protein

IDBP-595889.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNAPC3

Protein Name

small nuclear RNA activating complex, polypeptide 3, 50kDa

Synonyms

PTFbeta; SNAP50;

Species

Homo sapiens

Ensembl Protein

ENSP00000432393

InnateDB Gene

IDBG-51128 (SNAPC3)

Protein Structure

UniProt Annotation

Function

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. {ECO:0000269PubMed:12621023}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006383	transcription from RNA polymerase III promoter
GO:0009301	snRNA transcription
GO:0010467	gene expression