InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADAM11

Summary

InnateDB Protein

IDBP-596668.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAM11

Protein Name

ADAM metallopeptidase domain 11

Synonyms

MDC;

Species

Homo sapiens

Ensembl Protein

ENSP00000443773

InnateDB Gene

IDBG-54231 (ADAM11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding

Biological Process

GO:0006508	proteolysis
GO:0007229	integrin-mediated signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR006586 ADAM, cysteine-rich

PFAM

PF00008
PF01421
PF00200
PF08516

PRINTS

PR00289

PIRSF

SMART

SM00181
SM00050
SM00608

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt