InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP1R12A

Summary

InnateDB Protein

IDBP-596790.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP1R12A

Protein Name

protein phosphatase 1, regulatory subunit 12A

Synonyms

M130; MBS; MYPT1;

Species

Homo sapiens

Ensembl Protein

ENSP00000449514

InnateDB Gene

IDBG-49402 (PPP1R12A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	72 [view]
Protein-Protein	69 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004857	enzyme inhibitor activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0019208	phosphatase regulator activity
GO:0019901	protein kinase binding
GO:0071889	14-3-3 protein binding

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0006470	protein dephosphorylation
GO:0007067	mitotic nuclear division
GO:0007165	signal transduction
GO:0030155	regulation of cell adhesion
GO:0035507	regulation of myosin-light-chain-phosphatase activity
GO:0043086	negative regulation of catalytic activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051297	centrosome organization

Cellular Component

GO:0000776	kinetochore
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0015629	actin cytoskeleton
GO:0043292	contractile fiber
GO:0072357	PTW/PP1 phosphatase complex