Version 5.4
Homo sapiens Protein: SP7
Summary
InnateDB Protein IDBP-597294.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SP7
Protein Name Sp7 transcription factor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000441367
InnateDB Gene IDBG-36582 (SP7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0017151 DEAD/H-box RNA helicase binding
GO:0046872 metal ion binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060218 hematopoietic stem cell differentiation
GO:2000738 positive regulation of stem cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TDD2
PhosphoSite PhosphoSite-Q8TDD2
TrEMBL F8VV67
UniProt Splice Variant
Entrez Gene 121340
UniGene Hs.209402
RefSeq NP_001287766
HUGO HGNC:17321
OMIM 606633
CCDS CCDS73475
HPRD 05971
IMGT
EMBL AC073611 AF466179 AF477981 AK128520 AY150673 AY150674 BC101549 BC113613 CH471054
GenPept AAI01550 AAI13614 AAL84281 AAN85556 AAN85557 AAO33377 BAG54688 EAW96695 EAW96696 EAW96697

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca