Version 5.4
Homo sapiens Protein: AMPD2
Summary
InnateDB Protein IDBP-597372.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMPD2
Protein Name adenosine monophosphate deaminase 2
Synonyms PCH9; SPG63;
Species Homo sapiens
Ensembl Protein ENSP00000437164
InnateDB Gene IDBG-100855 (AMPD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0006188 IMP biosynthetic process
GO:0032264 IMP salvage
GO:0043101 purine-containing compound salvage
GO:0044281 small molecule metabolic process
GO:0052652 cyclic purine nucleotide metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
GO:0097009 energy homeostasis
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001365 Adenosine/AMP deaminase domain
IPR006329 AMP deaminase
PFAM PF00962
PRINTS
PIRSF PIRSF001251
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q01433
PhosphoSite PhosphoSite-Q01433
TrEMBL E9PIJ1
UniProt Splice Variant
Entrez Gene 271
UniGene Hs.82927
RefSeq NP_001244290
HUGO HGNC:469
OMIM 102771
CCDS CCDS58016
HPRD 11808
IMGT
EMBL AK296394 AK302939 AL355310 BC007711 BC075844 CH471122 M91029 S47833 U16267 U16268 U16269 U16270 U16271 U16272
GenPept AAA11725 AAA62126 AAA62127 AAB06511 AAC50306 AAC50307 AAC50308 AAC50309 AAD56302 AAD56303 AAH07711 AAH75844 BAG59062 BAG64097 CAI19305 CAI19307 EAW56396 EAW56399 EAW56401

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca