InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GIT2

Summary

InnateDB Protein

IDBP-597835.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GIT2

Protein Name

G protein-coupled receptor kinase interacting ArfGAP 2

Synonyms

CAT-2; CAT2;

Species

Homo sapiens

Ensembl Protein

ENSP00000448832

InnateDB Gene

IDBG-56520 (GIT2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	57 [view]
Protein-Protein	57 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding

Biological Process

GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001164 Arf GTPase activating protein
IPR002110 Ankyrin repeat
IPR013724 Spa2 homology (SHD) of GIT
IPR020683 Ankyrin repeat-containing domain
IPR022018 G protein-coupled receptor kinase-interacting protein 1 C term

PFAM