InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: APLP1

Summary

InnateDB Protein

IDBP-597839.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APLP1

Protein Name

amyloid beta (A4) precursor-like protein 1

Synonyms

APLP;

Species

Homo sapiens

Ensembl Protein

ENSP00000441501

InnateDB Gene

IDBG-45875 (APLP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 70 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	70 [view]
Protein-Protein	70 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008201	heparin binding
GO:0046914	transition metal ion binding

Biological Process

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR008154 Amyloidogenic glycoprotein, extracellular
IPR008155 Amyloidogenic glycoprotein
IPR011178 Amyloidogenic glycoprotein, copper-binding
IPR015849 Amyloidogenic glycoprotein, heparin-binding
IPR019543 Beta-amyloid precursor protein C-terminal
IPR024329 Amyloidogenic glycoprotein, E2 domain

PFAM

PF12924
PF02177
PF10515
PF12925

PRINTS

PR00203

PIRSF

SMART

SM00006

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt