Version 5.4
Homo sapiens Protein: BIRC2
Summary
InnateDB Protein IDBP-597963.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BIRC2
Protein Name baculoviral IAP repeat containing 2
Synonyms API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48;
Species Homo sapiens
Ensembl Protein ENSP00000434979
InnateDB Gene IDBG-69075 (BIRC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 184 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 184 [view]
Protein-Protein 179 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0042981 regulation of apoptotic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001315 CARD domain
IPR001370 Baculoviral inhibition of apoptosis protein repeat
IPR001841 Zinc finger, RING-type
IPR011029 Death-like domain
PFAM PF00619
PF00653
PF13639
PF14634
PRINTS
PIRSF
SMART SM00114
SM00238
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PNM6
UniProt Splice Variant
Entrez Gene 329
UniGene Hs.731943
RefSeq
HUGO HGNC:590
OMIM 601712
CCDS
HPRD 03419
IMGT
EMBL AP000942
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca