Version 5.4
Homo sapiens Protein: HDC
Summary
InnateDB Protein IDBP-598499.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HDC
Protein Name histidine decarboxylase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000440252
InnateDB Gene IDBG-11604 (HDC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 cellular amino acid metabolic process
GO:0019752 carboxylic acid metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002129 Pyridoxal phosphate-dependent decarboxylase
IPR010977 Aromatic-L-amino-acid decarboxylase
IPR015424 Pyridoxal phosphate-dependent transferase
PFAM PF00282
PRINTS PR00800
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7ZM01
UniProt Splice Variant
Entrez Gene 3067
UniGene Hs.1481
RefSeq
HUGO HGNC:4855
OMIM 142704
CCDS
HPRD 00817
IMGT
EMBL AC009753 AC022087 BC144173
GenPept AAI44174

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca