InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC44A1

Summary

InnateDB Protein

IDBP-598604.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC44A1

Protein Name

solute carrier family 44, member 1

Synonyms

CD92; CDW92; CHTL1; CTL1;

Species

Homo sapiens

Ensembl Protein

ENSP00000433072

InnateDB Gene

IDBG-79517 (SLC44A1)

Protein Structure

UniProt Annotation

Function

Choline transporter. May be involved in membrane synthesis and myelin production. {ECO:0000269PubMed:19357133}.

Subcellular Localization

Cell membrane {ECO:0000269PubMed:19357133}; Multi-pass membrane protein {ECO:0000269PubMed:19357133}. Mitochondrion outer membrane {ECO:0000269PubMed:19357133}; Multi- pass membrane protein {ECO:0000269PubMed:19357133}.

Disease Associations

Tissue Specificity

Expressed in various cells of the hematopoietic system. {ECO:0000269PubMed:11698453}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015220	choline transmembrane transporter activity

Biological Process

GO:0006644	phospholipid metabolic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0015871	choline transport
GO:0044281	small molecule metabolic process
GO:0046474	glycerophospholipid biosynthetic process
GO:0055085	transmembrane transport

Cellular Component

GO:0005741	mitochondrial outer membrane
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome