Version 5.4
Homo sapiens Protein: C8B
Summary
InnateDB Protein IDBP-598879.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C8B
Protein Name complement component 8, beta polypeptide
Synonyms C82;
Species Homo sapiens
Ensembl Protein ENSP00000440113
InnateDB Gene IDBG-99157 (C8B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 2 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005579 membrane attack complex
Protein Structure and Domains
PDB ID
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR001862 Membrane attack complex component/perforin/complement C9
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR020864 Membrane attack complex component/perforin (MACPF) domain
PFAM PF00090
PF00057
PF01823
PRINTS PR00764
PR00261
PIRSF
SMART SM00209
SM00192
SM00457
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5GY80
UniProt Splice Variant
Entrez Gene 732
UniGene Hs.702980
RefSeq NP_001265473
HUGO HGNC:1353
OMIM 120960
CCDS CCDS60151
HPRD 00410
IMGT
EMBL AL121998
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca