Version 5.4
Homo sapiens Protein: GPR161
Summary
InnateDB Protein IDBP-598890.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR161
Protein Name G protein-coupled receptor 161
Synonyms RE2;
Species Homo sapiens
Ensembl Protein ENSP00000437576
InnateDB Gene IDBG-104596 (GPR161)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0030819 positive regulation of cAMP biosynthetic process
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Cellular Component
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
GO:0060170 ciliary membrane
GO:0072372 primary cilium
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N6U8
PhosphoSite PhosphoSite-Q8N6U8
TrEMBL
UniProt Splice Variant
Entrez Gene 23432
UniGene Hs.271809
RefSeq NP_001254542
HUGO HGNC:23694
OMIM 612250
CCDS CCDS58044
HPRD 17070
IMGT
EMBL AF091890 AK056040 AK122656 AK298797 AK298850 AK299634 AL033532 AY275468 BC028163
GenPept AAC61598 AAH28163 AAP32300 BAG51611 BAG53646 BAH12873 BAH12884 BAH13082 CAI22622 CAI22623

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca