Version 5.4
Homo sapiens Protein: LGMN
Summary
InnateDB Protein IDBP-599840.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGMN
Protein Name legumain
Synonyms AEP; LGMN1; PRSC1;
Species Homo sapiens
Ensembl Protein ENSP00000451797
InnateDB Gene IDBG-17093 (LGMN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001096 Peptidase C13, legumain
PFAM PF01650
PRINTS PR00776
PIRSF PIRSF019663
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V5B2
UniProt Splice Variant
Entrez Gene 5641
UniGene Hs.741226
RefSeq
HUGO HGNC:9472
OMIM 602620
CCDS
HPRD 04017
IMGT
EMBL AL132987 AL136332
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca