InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CNTFR

Summary

InnateDB Protein

IDBP-59996.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CNTFR

Protein Name

ciliary neurotrophic factor receptor

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000242338

InnateDB Gene

IDBG-59992 (CNTFR)

Protein Structure

UniProt Annotation

Function

Binds to CNTF. The alpha subunit provides the receptor specificity.

Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Nervous system and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004897	ciliary neurotrophic factor receptor activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0019955	cytokine binding

Biological Process

GO:0007165	signal transduction
GO:0007399	nervous system development
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0019898	extrinsic component of membrane
GO:0031225	anchored component of membrane
GO:0097059	CNTFR-CLCF1 complex