Version 5.4
Homo sapiens Protein: LIG1
Summary
InnateDB Protein IDBP-600070.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIG1
Protein Name ligase I, DNA, ATP-dependent
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000445928
InnateDB Gene IDBG-60038 (LIG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 10 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
Biological Process
GO:0006266 DNA ligation
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR012308 DNA ligase, ATP-dependent, N-terminal
PFAM PF04675
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q76GR4
UniProt Splice Variant
Entrez Gene 3978
UniGene Hs.738849
RefSeq
HUGO HGNC:6598
OMIM 126391
CCDS
HPRD 00534
IMGT
EMBL AB103328 AC011466 AK303644
GenPept BAC81763 BAG64647

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca