InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HPGD

Summary

InnateDB Protein

IDBP-600432.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HPGD

Protein Name

hydroxyprostaglandin dehydrogenase 15-(NAD)

Synonyms

15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1;

Species

Homo sapiens

Ensembl Protein

ENSP00000438017

InnateDB Gene

IDBG-44946 (HPGD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004957	prostaglandin E receptor activity
GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0016491	oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0051287	NAD binding
GO:0070403	NAD+ binding

Biological Process

GO:0006693	prostaglandin metabolic process
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007565	female pregnancy
GO:0007567	parturition
GO:0008152	metabolic process
GO:0019369	arachidonic acid metabolic process
GO:0019371	cyclooxygenase pathway
GO:0019372	lipoxygenase pathway
GO:0030728	ovulation
GO:0044281	small molecule metabolic process
GO:0045786	negative regulation of cell cycle
GO:0055114	oxidation-reduction process
GO:0070493	thrombin receptor signaling pathway
GO:0097070	ductus arteriosus closure
GO:2001300	lipoxin metabolic process