InnateDB Protein
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IDBP-600446.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PKD1L2
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Protein Name
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polycystic kidney disease 1-like 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000436309
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InnateDB Gene
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IDBG-43476 (PKD1L2)
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Protein Structure
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Function |
May function as an ion-channel regulator. May function as a G-protein-coupled receptor. {ECO:0000269PubMed:15203210}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. {ECO:0000269PubMed:12782129}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002859
PKD/REJ-like protein
IPR013041
Coatomer/clathrin adaptor appendage, Ig-like subdomain
IPR014010
Egg jelly receptor, REJ-like
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PFAM |
PF02010
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7Z442
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PhosphoSite |
PhosphoSite-Q7Z442
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TrEMBL |
Q6AI51
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UniProt Splice Variant |
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Entrez Gene |
114780
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UniGene |
Hs.737982
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RefSeq |
NP_001265352
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HUGO |
HGNC:21715
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OMIM |
607894
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CCDS |
CCDS61999
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HPRD |
06990
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IMGT |
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EMBL |
AB067466
AC092718
AC131888
AK098052
AK127266
AK131378
AY164483
AY371495
BC004562
BC014157
CR627341
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GenPept |
AAH04562
AAH14157
AAO32796
AAQ73173
BAB67772
BAC05222
BAC86906
BAD18529
CAH10372
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