Version 5.4
Homo sapiens Protein: PLCZ1
Summary
InnateDB Protein IDBP-600488.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLCZ1
Protein Name phospholipase C, zeta 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000443762
InnateDB Gene IDBG-21958 (PLCZ1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
PFAM PF00388
PF00387
PRINTS
PIRSF
SMART SM00148
SM00149
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5H828
UniProt Splice Variant
Entrez Gene 89869
UniGene Hs.97542
RefSeq
HUGO HGNC:19218
OMIM 608075
CCDS
HPRD 06996
IMGT
EMBL AC087242
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca