Version 5.4
Homo sapiens Protein: NONO
Summary
InnateDB Protein IDBP-600810.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NONO
Protein Name non-POU domain containing, octamer-binding
Synonyms NMT55; NRB54; P54; P54NRB; PPP1R114;
Species Homo sapiens
Ensembl Protein ENSP00000441364
InnateDB Gene IDBG-75619 (NONO)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 157 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 157 [view]
Protein-Protein 155 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0001047 core promoter binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006397 mRNA processing
GO:0007623 circadian rhythm
GO:0008380 RNA splicing
GO:0042752 regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0016607 nuclear speck
GO:0042382 paraspeckles
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR012975 NOPS
PFAM PF00076
PF08075
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15233
PhosphoSite PhosphoSite-Q15233
TrEMBL
UniProt Splice Variant
Entrez Gene 4841
UniGene Hs.572371
RefSeq NP_001138882
HUGO HGNC:7871
OMIM 300084
CCDS CCDS55445
HPRD 02098
IMGT
EMBL AK297144 AL590762 BC002364 BC003129 BC012141 BC028299 BC069616 BC069639 CH471132 CR456761 L14599 U02493 U89867 Y11289 Y11290 Y11291 Y11292 Y11293 Y11294 Y11295 Y11296 Y11297 Y11298
GenPept AAA03427 AAC37578 AAC51852 AAH02364 AAH03129 AAH12141 AAH28299 AAH69616 AAH69639 BAH12508 CAA72157 CAG33042 EAX05298 EAX05299 EAX05300

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca