Homo sapiens Protein: MIXL1
Summary
InnateDB Protein IDBP-601115.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIXL1
Protein Name Mix paired-like homeobox
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000442439
InnateDB Gene IDBG-107018 (MIXL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 RNA polymerase II transcription factor binding
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0001190 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001706 endoderm formation
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006351 transcription, DNA-templated
GO:0007369 gastrulation
GO:0007492 endoderm development
GO:0007507 heart development
GO:0030097 hemopoiesis
GO:0035987 endodermal cell differentiation
GO:0042074 cell migration involved in gastrulation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048565 digestive tract development
GO:1901533 negative regulation of hematopoietic progenitor cell differentiation
GO:2000382 positive regulation of mesoderm development
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
PFAM PF00046
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H2W2
PhosphoSite PhosphoSite-Q9H2W2
TrEMBL
UniProt Splice Variant
Entrez Gene 83881
UniGene Hs.734947
RefSeq NP_001269331
HUGO HGNC:13363
OMIM 609852
CCDS CCDS60432
HPRD 10086
IMGT
EMBL AF211891 AF218357 AL592045 BC111974 BC113441 BC143784 CH471098
GenPept AAG35776 AAI11975 AAI13442 AAI43785 AAK01479 CAH71924 EAW69778