Version 5.4
Homo sapiens Protein: SMPDL3B
Summary
InnateDB Protein IDBP-601165.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMPDL3B
Protein Name sphingomyelin phosphodiesterase, acid-like 3B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000449450
InnateDB Gene IDBG-95108 (SMPDL3B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006685 sphingomyelin catabolic process
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like
PFAM PF00149
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8VWW8
UniProt Splice Variant
Entrez Gene 27293
UniGene Hs.123659
RefSeq
HUGO HGNC:21416
OMIM
CCDS
HPRD 15405
IMGT
EMBL AK293566 AL512288
GenPept BAG57037

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca