Version 5.4
Homo sapiens Protein: SOX5
Summary
InnateDB Protein IDBP-601444.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX5
Protein Name SRY (sex determining region Y)-box 5
Synonyms L-SOX5; L-SOX5B; L-SOX5F;
Species Homo sapiens
Ensembl Protein ENSP00000443520
InnateDB Gene IDBG-23504 (SOX5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 18 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0032332 positive regulation of chondrocyte differentiation
GO:0061036 positive regulation of cartilage development
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:2000741 positive regulation of mesenchymal stem cell differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P35711
PhosphoSite PhosphoSite-P35711
TrEMBL T2CYZ2
UniProt Splice Variant
Entrez Gene 6660
UniGene Hs.657542
RefSeq NP_001248344
HUGO HGNC:11201
OMIM 604975
CCDS CCDS58217
HPRD 18086
IMGT
EMBL AB081588 AB081589 AB081590 AB081591 AC087244 AC087260 AC087319 AC092864 AK074317 AK098610 AK303970 BC029220 BC035227 BC047665 BC060773 JX570584 S83308 X65662
GenPept AAB49537 AAH29220 AAH35227 AAH47665 AAH60773 AGV38565 BAB85048 BAC05353 BAC16233 BAC16234 BAC16235 BAC16236 BAH14086 CAA46613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca