Version 5.4
Homo sapiens Protein: DIXDC1
Summary
InnateDB Protein IDBP-601481.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIXDC1
Protein Name DIX domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000434130
InnateDB Gene IDBG-71136 (DIXDC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0043015 gamma-tubulin binding
Biological Process
GO:0021695 cerebellar cortex development
GO:0030900 forebrain development
GO:0043010 camera-type eye development
GO:0046328 regulation of JNK cascade
GO:0050772 positive regulation of axonogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0043025 neuronal cell body
GO:0043679 axon terminus
Protein Structure and Domains
PDB ID
InterPro IPR001715 Calponin homology domain
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF11971
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q155Q3
PhosphoSite PhosphoSite-Q155Q3
TrEMBL
UniProt Splice Variant
Entrez Gene 85458
UniGene Hs.655626
RefSeq NP_001265471
HUGO HGNC:23695
OMIM 610493
CCDS CCDS60957
HPRD 16804
IMGT
EMBL AB051522 AK055899 AP000907 BC033034 BC035509 BC041626 BC048294 BC064479 BC128600 CH471065 DQ642016
GenPept AAH33034 AAH35509 AAH41626 AAH48294 AAH64479 AAI28601 ABG25914 BAB21826 BAB71039 EAW67171

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca