InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CARS

Summary

InnateDB Protein

IDBP-602140.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CARS

Protein Name

cysteinyl-tRNA synthetase

Synonyms

CARS1; CYSRS; MGC:11246;

Species

Homo sapiens

Ensembl Protein

ENSP00000432619

InnateDB Gene

IDBG-23884 (CARS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.

Experimentally validated
Total	33 [view]
Protein-Protein	32 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004817	cysteine-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006423	cysteinyl-tRNA aminoacylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
IPR015413 Methionyl/Leucyl tRNA synthetase
IPR015803 Cysteine-tRNA ligase
IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase

PFAM

PF09334
PF01406

PRINTS

PR00983

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite