InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABR

Summary

InnateDB Protein

IDBP-602730.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABR

Protein Name

active BCR-related gene

Synonyms

MDB;

Species

Homo sapiens

Ensembl Protein

ENSP00000437429

InnateDB Gene

IDBG-14430 (ABR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0032321	positive regulation of Rho GTPase activity
GO:0035023	regulation of Rho protein signal transduction

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000198 Rho GTPase-activating protein domain
IPR000219 Dbl homology (DH) domain
IPR001849 Pleckstrin homology domain
IPR008936 Rho GTPase activation protein

PFAM

PF00168
PF00620
PF00621
PF00169

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00324
SM00325
SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt