Version 5.4
Homo sapiens Protein: SRGAP1
Summary
InnateDB Protein IDBP-603277.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRGAP1
Protein Name SLIT-ROBO Rho GTPase activating protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000437948
InnateDB Gene IDBG-44723 (SRGAP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR001060 FCH domain
IPR001452 SH3 domain
IPR004216 L-fucose/L-arabinose isomerase, C-terminal
IPR008936 Rho GTPase activation protein
IPR011511 Variant SH3 domain
PFAM PF00620
PF00611
PF00018
PF14604
PF07653
PRINTS PR00452
PIRSF
SMART SM00324
SM00055
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5EA48
UniProt Splice Variant
Entrez Gene 57522
UniGene Hs.613169
RefSeq XP_005269099
HUGO HGNC:17382
OMIM 606523
CCDS
HPRD 09406
IMGT
EMBL AC020611 AC025576 AC079866 AC084357 CH471054
GenPept EAW97122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca