Version 5.4
Homo sapiens Protein: POLR1B
Summary
InnateDB Protein IDBP-603520.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR1B
Protein Name polymerase (RNA) I polypeptide B, 128kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000437914
InnateDB Gene IDBG-66306 (POLR1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 35 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003899 DNA-directed RNA polymerase activity
GO:0032549 ribonucleoside binding
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6
IPR007641 RNA polymerase Rpb2, domain 7
IPR007642 RNA polymerase Rpb2, domain 2
IPR007645 RNA polymerase Rpb2, domain 3
IPR007647 RNA polymerase Rpb2, domain 5
IPR009674 RNA polymerase I, Rpa2 specific
PFAM PF00562
PF04560
PF04561
PF04565
PF04567
PF06883
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9BSR4
UniProt Splice Variant
Entrez Gene 84172
UniGene Hs.619285
RefSeq NP_001269705
HUGO HGNC:20454
OMIM 602000
CCDS CCDS62990
HPRD 06852
IMGT
EMBL AC012442 BC004882 BC073857
GenPept AAH04882 AAH73857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca