Version 5.4
Homo sapiens Protein: CPA3
Summary
InnateDB Protein IDBP-60398.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPA3
Protein Name carboxypeptidase A3 (mast cell)
Synonyms MC-CPA;
Species Homo sapiens
Ensembl Protein ENSP00000296046
InnateDB Gene IDBG-60396 (CPA3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0002002 regulation of angiotensin levels in blood
GO:0002003 angiotensin maturation
GO:0006508 proteolysis
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0030133 transport vesicle
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID
InterPro IPR000834 Peptidase M14, carboxypeptidase A
IPR003146 Proteinase inhibitor, carboxypeptidase propeptide
IPR009020 Proteinase inhibitor, propeptide
PFAM PF00246
PF02244
PRINTS PR00765
PIRSF
SMART SM00631
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P15088
PhosphoSite PhosphoSite-P15088
TrEMBL
UniProt Splice Variant
Entrez Gene 1359
UniGene Hs.646
RefSeq NP_001861
HUGO HGNC:2298
OMIM 114851
CCDS CCDS3138
HPRD 00270
IMGT
EMBL AC092979 BC012613 M27717 M73716 M73717 M73718 M73719 M73720 S40234
GenPept AAA35652 AAA59568 AAB22578 AAH12613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca