Version 5.4
Homo sapiens Protein: TM4SF1
Summary
InnateDB Protein IDBP-60709.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TM4SF1
Protein Name transmembrane 4 L six family member 1
Synonyms H-L6; L6; M3S1; TAAL6;
Species Homo sapiens
Ensembl Protein ENSP00000304277
InnateDB Gene IDBG-60707 (TM4SF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008661 L6 membrane
PFAM PF05805
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30408
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4071
UniGene Hs.740377
RefSeq NP_055035
HUGO HGNC:11853
OMIM 191155
CCDS CCDS3143
HPRD 01854
IMGT
EMBL BC008442 BC010166 CR456953 M90657
GenPept AAA36158 AAH08442 AAH10166 CAG33234

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca