InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: P2RY14

Summary

InnateDB Protein

IDBP-61503.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P2RY14

Protein Name

purinergic receptor P2Y, G-protein coupled, 14

Synonyms

BPR105; GPR105; P2Y14;

Species

Homo sapiens

Ensembl Protein

ENSP00000308361

InnateDB Gene

IDBG-61501 (P2RY14)

Protein Structure

UniProt Annotation

Function

Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. {ECO:0000269PubMed:10753868}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0045028	G-protein coupled purinergic nucleotide receptor activity
GO:0045029	UDP-activated nucleotide receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
GO:0045087	innate immune response (InnateDB)