InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GDPD1

Summary

InnateDB Protein

IDBP-61650.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GDPD1

Protein Name

glycerophosphodiester phosphodiesterase domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000284116

InnateDB Gene

IDBG-61648 (GDPD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:18991142}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Detected in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocytes. {ECO:0000269PubMed:16147865}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008081	phosphoric diester hydrolase activity
GO:0008889	glycerophosphodiester phosphodiesterase activity
GO:0046872	metal ion binding

Biological Process

GO:0006071	glycerol metabolic process
GO:0006629	lipid metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8N9F7

PhosphoSite

PhosphoSite-Q8N9F7

TrEMBL

J3QRR6

UniProt Splice Variant

Entrez Gene

284161

UniGene

Hs.735991

RefSeq

NP_872375

HUGO

HGNC:20883

OMIM

CCDS

CCDS11616

HPRD

08223

IMGT

EMBL

AC091059 AC099850 AK094770 AY271346 BC034432 CH471109 EU192951

GenPept

AAH34432 AAQ01751 ABW73991 BAC04419 EAW94412