InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lpar2

Summary

InnateDB Protein

IDBP-619787.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lpar2

Protein Name

lysophosphatidic acid receptor 2

Synonyms

Edg4; IPA2; LPA2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128261

InnateDB Gene

IDBG-160734 (Lpar2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0030165	PDZ domain binding
GO:0070915	lysophosphatidic acid receptor activity

Biological Process

GO:0000187	activation of MAPK activity
GO:0007186	G-protein coupled receptor signaling pathway
GO:0035025	positive regulation of Rho protein signal transduction
GO:0043410	positive regulation of MAPK cascade

Cellular Component

GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030139	endocytic vesicle

Protein Structure and Domains

PDB ID

MGI:1858422

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001671 Melanocortin/ACTH receptor
IPR002277 Lysophosphatidic acid receptor EDG-2
IPR004061 Sphingosine 1-phosphate receptor
IPR004065 Lysophosphatidic acid receptor
IPR004066 Lysophosphatidic acid receptor EDG-4
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00534
PR01148
PR01523
PR01527
PR01528

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite