InnateDB Protein
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IDBP-619838.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Banf1
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Protein Name
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barrier to autointegration factor 1
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Synonyms
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Baf; Bcrp1; L2bp1/Baf;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000126202
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InnateDB Gene
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IDBG-131341 (Banf1)
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Protein Structure
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Function |
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Chromosome {ECO:0000250}. Note=Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. The phosphorylated form (by VRK1) shows a cytoplasmic localization (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
54 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1346330
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InterPro |
IPR004122
Barrier- to-autointegration factor, BAF
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PFAM |
PF02961
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PRINTS |
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PIRSF |
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SMART |
SM01023
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TIGRFAMs |
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Modification |
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SwissProt |
O54962
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PhosphoSite |
PhosphoSite-O54962
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23825
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UniGene |
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RefSeq |
NP_001273537
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MGI ID |
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MGI Symbol |
Banf1
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OMIM |
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CCDS |
CCDS29458
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HPRD |
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IMGT |
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EMBL |
AB025349
AF037080
AK003025
AK004212
AK010257
AK011079
AK011100
AK012588
AK088896
BC003709
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GenPept |
AAC40032
AAH03709
BAA83102
BAB22518
BAB23223
BAB26800
BAB27383
BAB27397
BAB28337
BAC40639
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