Version 5.4
Mus musculus Protein: Pola2
Summary
InnateDB Protein IDBP-619858.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pola2
Protein Name polymerase (DNA directed), alpha 2
Synonyms AI573378;
Species Mus musculus
Ensembl Protein ENSMUSP00000128866
InnateDB Gene IDBG-133634 (Pola2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
Cellular Component
GO:0005634 nucleus
GO:0005658 alpha DNA polymerase:primase complex
Protein Structure and Domains
PDB ID MGI:99690
InterPro IPR007185 DNA polymerase alpha/epsilon, subunit B
IPR013627 DNA polymerase alpha, subunit B N-terminal
IPR016722 DNA polymerase alpha, subunit B
PFAM PF04042
PF08418
PRINTS
PIRSF PIRSF018300
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C2T6
UniProt Splice Variant
Entrez Gene 18969
UniGene
RefSeq NP_001157529
MGI ID
MGI Symbol Pola2
OMIM
CCDS CCDS50362
HPRD
IMGT
EMBL AC127271 AK087989
GenPept BAC40078

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca